sulphonylurea

简明释义

英[ˌsʌl fə nɪl ˈjʊər i ə]美[ˌsʌl fə nɪl ˈjʊər i ə]

n. 磺脲（一种治糖尿病的口服药）

英英释义

单词用法

同义词

反义词

例句

1.Glibenclamide (glyburide) binds to sulphonylurea receptors, the regulatory subunit of ATP-sensitive K + channels prominently expressed in the ER.

格列本脲能结合磺脲受体，该受体是主要在ER中表达的AT P敏感的钾通道的调节亚基。

2.Glibenclamide (glyburide) binds to sulphonylurea receptors, the regulatory subunit of ATP-sensitive K + channels prominently expressed in the ER.

格列本脲能结合磺脲受体，该受体是主要在ER中表达的AT P敏感的钾通道的调节亚基。

3.Aim to develop a method for identification of sulphonylurea illegally added into the antidiabetic food for health care.

目的建立降糖保健食品中非法添加磺酰脲类降糖药的定性检测方法。

4.Patients with type 2 diabetes often use sulphonylurea to help control their blood sugar levels.

2型糖尿病患者通常使用sulphonylurea来帮助控制血糖水平。

5.The doctor prescribed sulphonylurea as part of the patient's diabetes management plan.

医生开了sulphonylurea作为患者糖尿病管理计划的一部分。

6.Side effects of sulphonylurea may include weight gain and hypoglycemia.

sulphonylurea的副作用可能包括体重增加和低血糖。

7.It is important for patients to monitor their blood glucose levels when taking sulphonylurea.

患者在服用sulphonylurea时，监测血糖水平非常重要。

8.Some patients may experience an allergic reaction to sulphonylurea.

一些患者可能对sulphonylurea产生过敏反应。

作文

The management of diabetes has evolved significantly over the years, with various treatment options available to help individuals maintain their blood glucose levels. One important class of medications used in the treatment of type 2 diabetes is known as sulphonylurea. These drugs play a crucial role in stimulating insulin secretion from the pancreas, thereby lowering blood sugar levels in patients suffering from this chronic condition. Understanding how sulphonylurea works and its implications for patient care is essential for both healthcare providers and patients alike. sulphonylurea medications have been in use since the 1950s and are considered one of the first oral antidiabetic agents. They work by binding to specific receptors on pancreatic beta cells, which leads to an increase in insulin release. This mechanism is particularly beneficial for individuals whose bodies still produce some insulin but are unable to use it effectively due to insulin resistance. By enhancing insulin secretion, sulphonylurea helps to improve glycemic control and reduce the risk of complications associated with high blood sugar levels. Despite their effectiveness, it is important to recognize that sulphonylurea medications are not suitable for everyone. Patients who have certain health conditions, such as severe liver or kidney impairment, may not be ideal candidates for these drugs. Additionally, there is a risk of hypoglycemia, or low blood sugar, which can occur if the medication stimulates too much insulin release or if meals are skipped. Therefore, it is crucial for patients to work closely with their healthcare providers to determine the best treatment plan tailored to their individual needs. Another consideration when using sulphonylurea is its potential impact on weight. Some studies suggest that these medications may lead to weight gain in certain patients, which can be counterproductive for those who are already overweight or obese. As a result, healthcare providers often weigh the benefits and risks of using sulphonylurea in conjunction with lifestyle modifications, such as diet and exercise, to achieve optimal outcomes for their patients. In conclusion, sulphonylurea represents a valuable option in the pharmacological management of type 2 diabetes. Its ability to stimulate insulin secretion makes it an effective choice for many patients. However, careful consideration must be given to individual patient circumstances, potential side effects, and overall treatment goals. As diabetes continues to be a growing global health concern, understanding the role of medications like sulphonylurea is vital for improving patient care and outcomes. By fostering a collaborative approach between patients and healthcare providers, we can ensure that diabetes management is both effective and sustainable in the long term.

糖尿病的管理在过去几年中发生了显著变化，现有多种治疗选择帮助个人维持血糖水平。其中一种重要的药物类别被称为sulphonylurea。这些药物在刺激胰腺分泌胰岛素方面发挥着关键作用，从而降低患有这种慢性疾病的患者的血糖水平。理解sulphonylurea的工作原理及其对患者护理的影响，对医疗提供者和患者而言都是至关重要的。 sulphonylurea药物自1950年代以来一直在使用，被认为是首批口服抗糖尿病药物之一。它们通过与胰腺β细胞上的特定受体结合来发挥作用，从而增加胰岛素的释放。这一机制对于那些身体依然产生一些胰岛素但由于胰岛素抵抗而无法有效利用的个体尤其有益。通过增强胰岛素分泌，sulphonylurea有助于改善血糖控制并降低高血糖水平相关并发症的风险。 尽管效果显著，但需要认识到sulphonylurea药物并不适合所有人。患有某些健康状况的患者，例如严重的肝脏或肾脏损害，可能不是这些药物的理想候选者。此外，低血糖的风险也存在，这可能会发生在药物刺激过多的胰岛素释放或跳过餐食时。因此，患者与医疗提供者密切合作，以确定最适合其个人需求的治疗计划至关重要。 使用sulphonylurea时另一个考虑因素是其对体重的潜在影响。一些研究表明，这些药物可能导致某些患者体重增加，而这对已经超重或肥胖的人来说可能是适得其反的。因此，医疗提供者通常会权衡使用sulphonylurea与生活方式改变（如饮食和锻炼）相结合的好处与风险，以实现患者的最佳结果。 总之，sulphonylurea代表了2型糖尿病药物管理中的一种宝贵选择。它刺激胰岛素分泌的能力使其成为许多患者的有效选择。然而，必须仔细考虑个体患者的情况、潜在的副作用和整体治疗目标。随着糖尿病继续成为全球健康关注的焦点，理解像sulphonylurea这样的药物的作用对于改善患者护理和结果至关重要。通过促进患者与医疗提供者之间的合作，我们可以确保糖尿病管理在长期内既有效又可持续。