trimethadione
简明释义
英[ˌtraɪmeθəˈdaɪəʊn]美[traɪˌmeθəˈdaɪon]
n. 三甲双酮(一种抗癫痫药)
英英释义
Trimethadione is a medication used primarily as an anticonvulsant to control seizures, particularly in the treatment of epilepsy. | 三甲基二酮是一种主要用于抗癫痫药物,用于控制癫痫发作,特别是在癫痫的治疗中。 |
单词用法
Trimethadione剂量 | |
Trimethadione副作用 | |
开处方trimethadione | |
监测trimethadione水平 |
同义词
三甲氧二酮 | 三甲氧二酮被用作抗癫痫药物。 | ||
二酮 | Dione compounds are often studied in organic chemistry for their reactivity. | 二酮化合物常在有机化学中研究其反应性。 |
反义词
兴奋剂 | 咖啡因是咖啡中常见的兴奋剂。 | ||
激活剂 | Adrenaline acts as an activator in the fight-or-flight response. | 肾上腺素在战斗或逃跑反应中起到激活剂的作用。 |
例句
1.When mice got the medications before noise exposure, only trimethadione, not ethosuximide, significantly reduced subsequent hearing loss.
当老鼠在噪声暴露之前服药,仅仅是三甲双酮而不是乙琥胺显著的减少了随后的听力丧失。
2.When mice got the medications before noise exposure, only trimethadione, not ethosuximide, significantly reduced subsequent hearing loss.
当老鼠在噪声暴露之前服药,仅仅是三甲双酮而不是乙琥胺显著的减少了随后的听力丧失。
3.The doctor prescribed trimethadione for the patient's seizure management.
医生为患者的癫痫管理开了三甲氧二酮。
4.Patients taking trimethadione should be monitored for potential side effects.
服用三甲氧二酮的患者应监测潜在的副作用。
5.Before starting trimethadione, the patient was informed about its interactions with other medications.
在开始服用三甲氧二酮之前,患者被告知其与其他药物的相互作用。
6.The therapeutic effects of trimethadione can vary from person to person.
三甲氧二酮的治疗效果因人而异。
7.In clinical trials, trimethadione showed significant efficacy in controlling seizures.
在临床试验中,三甲氧二酮在控制癫痫方面显示出显著的疗效。
作文
Trimethadione is a medication that has been used primarily in the treatment of epilepsy, particularly in cases where other medications have failed to provide adequate control over seizures. It belongs to a class of drugs known as anticonvulsants, which work by stabilizing electrical activity in the brain. The chemical structure of trimethadione includes three methyl groups attached to a dione, which contributes to its pharmacological properties. This unique structure allows trimethadione to interact with various neurotransmitter systems, ultimately helping to reduce the frequency and severity of seizures. The history of trimethadione dates back to the mid-20th century when it was first synthesized. Its introduction into clinical practice provided an alternative for patients who did not respond well to traditional antiepileptic drugs. One of the notable advantages of trimethadione is its relatively low toxicity compared to other anticonvulsants, making it a preferred choice for certain populations, including children. However, like any medication, trimethadione is not without its side effects. Patients may experience dizziness, drowsiness, or gastrointestinal disturbances. In some cases, prolonged use can lead to more severe complications such as blood disorders or liver dysfunction. Therefore, it is crucial for healthcare providers to monitor patients closely while they are on this medication. The mechanism of action of trimethadione involves the modulation of neuronal excitability. By enhancing the inhibitory effects of gamma-aminobutyric acid (GABA), a primary inhibitory neurotransmitter in the brain, trimethadione helps to prevent the abnormal electrical discharges that characterize seizures. This makes it an effective option for managing seizure disorders, especially in individuals who have not achieved adequate control with other treatments. Despite its benefits, trimethadione is not commonly used as a first-line treatment for epilepsy today. The development of newer anticonvulsant medications with fewer side effects and more targeted mechanisms has led to a decline in the use of older drugs like trimethadione. Nevertheless, it remains an important part of the therapeutic arsenal for specific patient populations. In conclusion, trimethadione is a significant medication in the field of epilepsy treatment. While it has its limitations and potential side effects, its role in providing relief for patients who struggle with seizures cannot be understated. As research continues to evolve, the understanding of trimethadione and its applications may also expand, potentially leading to new insights into its use and effectiveness in various clinical scenarios. For patients and healthcare providers alike, being informed about trimethadione is essential for making educated decisions regarding epilepsy management and ensuring optimal outcomes for those affected by this challenging condition.
三甲氧嗪是一种主要用于治疗癫痫的药物,特别是在其他药物未能有效控制癫痫发作的情况下。它属于抗癫痫药物的一类,这类药物通过稳定大脑中的电活动来发挥作用。trimethadione的化学结构包括三个甲基团与一个二酮相连,这一结构对其药理特性有重要影响。这种独特的结构使得trimethadione能够与多种神经递质系统相互作用,最终帮助减少癫痫发作的频率和严重程度。 trimethadione的历史可以追溯到20世纪中叶,当时它首次被合成。它的临床应用为那些对传统抗癫痫药物反应不佳的患者提供了替代方案。trimethadione的一个显著优点是与其他抗癫痫药物相比,其毒性相对较低,使其成为某些人群(包括儿童)的首选。 然而,像任何药物一样,trimethadione也并非没有副作用。患者可能会出现头晕、嗜睡或胃肠道不适。在某些情况下,长期使用可能导致更严重的并发症,如血液疾病或肝功能障碍。因此,医疗提供者在患者服用此药期间密切监测至关重要。 trimethadione的作用机制涉及神经元兴奋性的调节。通过增强γ-氨基丁酸(GABA)的抑制效应,GABA是大脑中的主要抑制性神经递质,trimethadione帮助防止特征性癫痫发作的异常电放电。这使得它在管理癫痫疾病方面成为有效的选择,尤其是对于那些未能通过其他治疗获得充分控制的个体。 尽管有其好处,trimethadione今天并不常作为癫痫的一线治疗。随着新型抗癫痫药物的开发,它们副作用更少、机制更具针对性,导致像trimethadione这样的旧药物使用量下降。然而,它仍然是特定患者群体治疗武器库中的重要组成部分。 总之,trimethadione在癫痫治疗领域中具有重要意义。尽管它存在局限性和潜在副作用,但它在为那些苦于癫痫发作的患者提供缓解方面的作用不可小觑。随着研究的不断发展,对trimethadione及其应用的理解也可能会扩展,可能会导致对其在各种临床场景中使用和有效性的新的见解。对于患者和医疗提供者而言,了解trimethadione至关重要,以便做出明智的癫痫管理决策,并确保那些受此挑战性疾病影响者的最佳结果。
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