uricase

简明释义

英[ˈjʊərɪkeɪs]美[ˈjʊrɪkeɪs]

n. [生化] 尿酸酶

英英释义

单词用法

同义词

反义词

例句

1.Objective to characterize an extracellular uricase from Bacillus fastidious (ATCC 26904) and to evaluate its efficiency for direct kinetic assay of serum uric acid.

目的考察苛求芽孢杆菌(atcc 26904)分泌型尿酸酶的特性和将其应用于直接动力学尿酸酶法测定血清尿酸的有效性。

2.Objective to characterize an extracellular uricase from Bacillus fastidious (ATCC 26904) and to evaluate its efficiency for direct kinetic assay of serum uric acid.

目的考察苛求芽孢杆菌(atcc 26904)分泌型尿酸酶的特性和将其应用于直接动力学尿酸酶法测定血清尿酸的有效性。

3.Hershfield developed a new uric-acid-lowering drug called pEG-Uricase, which is now in clinical trials.

Hershfield研制了一种新的名为pEG - Uricase的降尿酸药现在临床试验中。

4.The enzyme uricase is crucial for breaking down uric acid in the body.

酶尿酸酶对于分解体内的尿酸至关重要。

5.Patients with gout often have low levels of uricase activity.

痛风患者通常有低水平的尿酸酶活性。

6.Research shows that increasing uricase levels can help manage hyperuricemia.

研究表明，提高尿酸酶水平可以帮助管理高尿酸血症。

7.Some medications aim to mimic the action of uricase to lower uric acid levels.

一些药物旨在模仿尿酸酶的作用，以降低尿酸水平。

8.The genetic mutation affects the production of uricase in certain individuals.

遗传突变影响某些个体中尿酸酶的产生。

作文

Uric acid is a compound that can be found in the human body and is produced when the body breaks down purines, which are substances found in certain foods. While uric acid is typically excreted through urine, excessive levels can lead to various health issues, such as gout and kidney stones. To manage these conditions, medical science has introduced various treatments, one of which involves the use of an enzyme known as uricase (尿酸酶). This enzyme plays a crucial role in the metabolism of uric acid. Specifically, uricase converts uric acid into allantoin, a more soluble compound that can be easily eliminated from the body. The discovery of uricase has significantly advanced our understanding of how to treat hyperuricemia, a condition characterized by high levels of uric acid in the blood. By harnessing the power of uricase, doctors can help patients lower their uric acid levels, thereby reducing the risk of gout attacks and other related complications. For instance, medications that contain recombinant uricase have been developed and are used to treat patients who do not respond well to traditional therapies. These treatments have shown promising results, providing relief to many individuals suffering from chronic gout. Despite its benefits, the use of uricase is not without challenges. Some patients may experience allergic reactions or other side effects when treated with uricase-based therapies. Additionally, the cost of these treatments can be prohibitive for some individuals, limiting access to this effective solution. Therefore, ongoing research is essential to improve the safety and affordability of uricase therapies. In conclusion, uricase (尿酸酶) is a vital enzyme that aids in the breakdown of uric acid, offering a therapeutic option for those suffering from elevated uric acid levels. As we continue to explore the potential of uricase in medical treatments, it is crucial to balance efficacy with safety and accessibility. Through further research and development, we can hope to enhance the quality of life for individuals affected by conditions associated with high uric acid levels, ensuring they receive the care they need without undue burden on their finances or health. The future of uricase therapy looks promising, and with continued advancements, it may become a standard part of treatment protocols for managing hyperuricemia and its related complications.

尿酸是人体内的一种化合物，产生于身体分解嘌呤时，嘌呤是一种在某些食物中发现的物质。虽然尿酸通常通过尿液排出，但过量的尿酸水平可能导致多种健康问题，如痛风和肾结石。为了管理这些疾病，医学科学引入了多种治疗方法，其中一种涉及使用一种被称为尿酸酶（uricase）的酶。这种酶在尿酸的代谢中起着至关重要的作用。具体来说，尿酸酶将尿酸转化为尿囊素，这是一种更易溶解的化合物，可以轻松地从体内排出。 尿酸酶的发现显著推动了我们对如何治疗高尿酸血症的理解，这是一种以血液中尿酸水平升高为特征的疾病。通过利用尿酸酶的力量，医生可以帮助患者降低尿酸水平，从而减少痛风发作和其他相关并发症的风险。例如，已经开发出含有重组尿酸酶的药物，并用于治疗对传统疗法反应不佳的患者。这些治疗显示出良好的效果，为许多遭受慢性痛风的个体提供了缓解。 尽管有其好处，使用尿酸酶并非没有挑战。一些患者在接受尿酸酶治疗时可能会出现过敏反应或其他副作用。此外，这些治疗的费用可能对某些个体来说是负担沉重的，限制了他们获得这种有效解决方案的机会。因此，持续的研究对于提高尿酸酶疗法的安全性和可负担性至关重要。 总之，尿酸酶（uricase）是一种重要的酶，帮助分解尿酸，为那些尿酸水平升高的人提供了一种治疗选择。随着我们继续探索尿酸酶在医疗治疗中的潜力，平衡疗效、安全性和可及性至关重要。通过进一步的研究和开发，我们希望改善受到高尿酸水平相关疾病影响的个体的生活质量，确保他们在不对财务或健康造成过大负担的情况下获得所需的护理。尿酸酶疗法的未来看起来很有希望，随着不断的进步，它可能成为管理高尿酸血症及其相关并发症的标准治疗方案的一部分。