vinblastine

简明释义

英[vɪnˈblæstiːn]美[vɪnˈblæsˌtin]

n. 长春花碱（一种抗肿瘤药）

英英释义

单词用法

同义词

反义词

例句

1.There are more than 100 kinds of alkaloids in vinca plant, including anhydrovinblastine, vinblastine, vincristine and other anti-tumor medicine used in clinic, etc.

如果对长春花的研究不是应用药理学方法的话，长春新碱的发现恐怕还要推迟好多年。

2.There are more than 100 kinds of alkaloids in vinca plant, including anhydrovinblastine, vinblastine, vincristine and other anti-tumor medicine used in clinic, etc.

如果对长春花的研究不是应用药理学方法的话，长春新碱的发现恐怕还要推迟好多年。

3.The vinblastine content was increased markedly in the supplementary UV-B radiation, and which were increased further when the nitrogen supply increased.

氮供应增加和UV-B辐射增强共同作用时，长春花叶片中长春碱的含量较其单独作用时均显著增加。

4.Conclusions The process is simple and reasonable with good reproducibility. It is effective to enrich highly purified vinblastine and vincristine.

结论该工艺简便合理，重复性良好，能得到高纯度的长春碱和长春新碱。

5.Objective To establish TK gene mutation assay using human lymphoblastoid cell line TK6 and to study the genotoxic mechanism of Vinblastine(VBL).

目的建立用人类淋巴母细胞TK 6检测纺锤体毒物——长春花碱的TK基因突变试验方法，同时探讨长春花碱的遗传毒性分子机理。

6.Several semisynthesis vinblastine analogues were prepared and lots of them have pharmacological activities, some even changed significantly.

目前人们已经合成了一系列长春碱类衍生物，其中大多数具有药理活性，有一些甚至产生极大变化。

7.Objective To optimize the technological parameters of separation and purification of vinblastine and vincristine from Gatharanthus Roseus.

目的优选分离纯化长春花中长春碱和长春新碱的最佳工艺参数。

8.For local lesions, injection therapy with vinblastine has been used with some success.

对于局部性病变，采用长春碱注射疗法已获得了一些成功。

9.Antitumor drug vinorelbine tartrate was synthesised from vinblastine sulfate in 15.

从硫酸长春碱合成抗癌药酒石酸长春瑞宾，总收率15。

10.The doctor prescribed vinblastine to treat the patient's lymphoma.

医生给患者开了长春新碱来治疗淋巴瘤。

11.During the chemotherapy session, the nurse administered vinblastine through an IV.

在化疗过程中，护士通过静脉注射给药了长春新碱。

12.Research shows that vinblastine can effectively inhibit cancer cell growth.

研究表明，长春新碱可以有效抑制癌细胞生长。

13.Patients receiving vinblastine often experience side effects such as nausea.

接受长春新碱治疗的患者常常会出现恶心等副作用。

14.The oncologist explained how vinblastine works at the cellular level.

肿瘤科医生解释了长春新碱在细胞层面的作用机制。

作文

Vinblastine is a powerful chemotherapeutic agent that has been used in the treatment of various types of cancer. It is derived from the periwinkle plant, specifically from the species Catharanthus roseus. This drug works by inhibiting cell division, which is crucial for the growth and spread of cancer cells. The mechanism of action of vinblastine (长春花碱) involves binding to tubulin, a protein that is essential for the formation of microtubules. Microtubules are necessary for mitosis, the process by which a cell divides into two daughter cells. By preventing the formation of these structures, vinblastine effectively halts the proliferation of cancer cells, making it an invaluable tool in oncology. The use of vinblastine (长春花碱) can be traced back to the mid-20th century when it was first isolated and studied for its potential medicinal properties. Since then, it has become a cornerstone in the treatment regimens for several malignancies, including Hodgkin's lymphoma, non-Hodgkin lymphoma, and testicular cancer. Its effectiveness in combination with other chemotherapy agents has significantly improved patient outcomes and survival rates. However, like many chemotherapeutic agents, vinblastine (长春花碱) is not without side effects. Patients undergoing treatment may experience a range of adverse reactions, including nausea, vomiting, hair loss, and increased risk of infection due to its immunosuppressive effects. These side effects arise because vinblastine does not exclusively target cancer cells; it can also affect normal, rapidly dividing cells in the body, such as those in the bone marrow and gastrointestinal tract. Despite these challenges, the discovery and application of vinblastine (长春花碱) represent a significant advancement in cancer therapy. Ongoing research continues to explore ways to enhance its effectiveness while minimizing side effects. For instance, scientists are investigating targeted delivery systems that could allow vinblastine (长春花碱) to home in on cancer cells more precisely, sparing healthy tissues from damage. In conclusion, vinblastine (长春花碱) plays an essential role in the fight against cancer. Its ability to disrupt cell division makes it a potent weapon in the oncologist's arsenal. While the side effects can be challenging for patients, the benefits of using vinblastine (长春花碱) in combination with other treatments have led to improved survival rates for many individuals battling cancer. As research progresses, there is hope that future advancements will further enhance the efficacy and safety of this remarkable drug, ultimately leading to better outcomes for patients worldwide.

长春花碱是一种强效的化疗药物，已被用于治疗多种类型的癌症。它源自长春花植物，特别是来自Catharanthus roseus物种。这种药物通过抑制细胞分裂来发挥作用，这对于癌细胞的生长和扩散至关重要。vinblastine（长春花碱）的作用机制涉及与微管蛋白结合，微管蛋白是微管形成所必需的蛋白质。微管对于有丝分裂至关重要，即细胞分裂成两个子细胞的过程。通过阻止这些结构的形成，vinblastine有效地停止了癌细胞的增殖，使其成为肿瘤学中不可或缺的工具。 vinblastine（长春花碱）的使用可以追溯到20世纪中叶，当时它首次被分离并研究其潜在的药用特性。从那时起，它已成为几种恶性肿瘤治疗方案的基石，包括霍奇金淋巴瘤、非霍奇金淋巴瘤和睾丸癌。它与其他化疗药物联合使用的有效性显著改善了患者的结果和生存率。 然而，与许多化疗药物一样，vinblastine（长春花碱）并非没有副作用。接受治疗的患者可能会经历一系列不良反应，包括恶心、呕吐、脱发和由于免疫抑制作用而增加感染风险。这些副作用的产生是因为vinblastine并不专门靶向癌细胞；它也会影响身体内正常的快速分裂细胞，例如骨髓和胃肠道中的细胞。 尽管面临这些挑战，vinblastine（长春花碱）的发现和应用代表了癌症治疗的重大进展。持续的研究继续探索增强其有效性同时最小化副作用的方法。例如，科学家们正在研究靶向递送系统，可以使vinblastine（长春花碱）更精确地定位癌细胞，从而保护健康组织免受损伤。 总之，vinblastine（长春花碱）在抗击癌症中发挥着重要作用。它破坏细胞分裂的能力使其成为肿瘤学家武器库中的一种强大武器。尽管副作用可能对患者造成挑战，但使用vinblastine（长春花碱）与其他治疗方法联合的好处使许多癌症患者的生存率得到了改善。随着研究的进展，人们希望未来的进步将进一步提高这种非凡药物的有效性和安全性，最终为全球患者带来更好的结果。