zidovudine

简明释义

英[zaɪˈdɒvjʊˌdiːn]美[zɪˈdovjʊˌdin]

n. 齐多夫定（抗艾滋病药物）；叠氮胸苷；叠氮胸腺

英英释义

单词用法

同义词

反义词

例句

1.Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore, use of zidovudine in combination with Stavudine is not recommended.

齐多夫定会竞争性抑制司他夫定的磷酸酰化，因此禁止与齐多夫定联合用药。

2.Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore, use of zidovudine in combination with Stavudine is not recommended.

齐多夫定会竞争性抑制司他夫定的磷酸酰化，因此禁止与齐多夫定联合用药。

3.Methods to develop zidovudine tablets with the technology of wet method pelletization and to determine the content of zidovudine tablets by HPLC.

方法以湿法制粒工艺制备齐多夫定片，采用高效液相色谱法对其进行含量测定。

4.The present invention relates to one kind of polyethylene glycol modified zidovudine conjugate and its preparation process and application.

本发明涉及一种聚乙二醇修饰齐多夫定缀合物及其制备方法与应用。

5.The invention discloses application of zidovudine lipid derivative in medicaments for treating virus associated diseases.

本发明公开了齐多夫定脂质衍生物在治疗与病毒有关疾病药品中的应用。

6.A few drugs have harmful effects when used together and should not be combined (an example is stavudine and zidovudine).

某药物一起使用时的会产生有害影响，不应组合使用(例如司他夫定和齐多夫定)。

7.Zidovudine (AZT) or Tenofovir (TDF) are recommended as less toxic and equally effective alternatives.

建议使用毒性更小但效果相同的齐多夫定(AZT)或泰诺·福韦(TDF)作为替代品。

8.Objective to develop zidovudine tablets and to study its quality-control method.

目的制备齐多夫定片并探讨其质量控制方法。

9.The doctor prescribed zidovudine for the patient diagnosed with HIV.

医生为被诊断为HIV的患者开了齐多夫定。

10.Research shows that zidovudine can help reduce the viral load in patients.

研究表明，齐多夫定可以帮助降低患者的病毒载量。

11.Patients taking zidovudine should be monitored for potential side effects.

服用齐多夫定的患者应监测潜在的副作用。

12.In combination therapy, zidovudine is often used alongside other antiretroviral drugs.

在联合治疗中，齐多夫定通常与其他抗逆转录病毒药物一起使用。

13.The efficacy of zidovudine has been well-documented in clinical trials.

齐多夫定的有效性在临床试验中得到了充分证明。

作文

Zidovudine, known as 齐多夫定 in Chinese, is an antiretroviral medication that has played a significant role in the treatment of HIV/AIDS. Initially approved by the FDA in 1987, zidovudine was the first drug to be used in the fight against the human immunodeficiency virus (HIV). The development of zidovudine marked a turning point in the history of HIV treatment, offering hope to millions of people living with the virus. Its primary function is to inhibit the reverse transcriptase enzyme, which is crucial for the replication of HIV. By blocking this enzyme, zidovudine prevents the virus from multiplying and helps to reduce the viral load in the body. The introduction of zidovudine was met with enthusiasm, as it was the first effective treatment option available. Before its approval, individuals diagnosed with HIV had limited choices and faced a grim prognosis. However, the advent of zidovudine changed the landscape of HIV treatment, allowing patients to manage their condition more effectively. It is often used in combination with other antiretroviral drugs to create a highly active antiretroviral therapy (HAART) regimen, which is more effective than any single medication alone. Despite its benefits, zidovudine is not without side effects. Common adverse reactions include nausea, headache, and fatigue. In some cases, long-term use of zidovudine can lead to more severe complications, such as bone marrow suppression, which can result in anemia and other blood-related issues. Therefore, healthcare providers must monitor patients closely and adjust treatment plans as necessary to mitigate these risks. Another critical aspect of zidovudine is its role in preventing mother-to-child transmission of HIV during childbirth. Pregnant women who are HIV-positive can take zidovudine to significantly reduce the risk of passing the virus to their newborns. This has been a groundbreaking advancement in public health, as it allows for the possibility of delivering healthy, HIV-negative babies. In conclusion, zidovudine represents a cornerstone in the treatment of HIV/AIDS. While it has its limitations and potential side effects, its impact on the lives of those affected by HIV cannot be overstated. As research continues, new and improved treatments are being developed, but zidovudine remains a vital part of the therapeutic arsenal against HIV. Understanding the significance of zidovudine and its role in managing this chronic condition is essential for both healthcare professionals and patients alike. With ongoing advancements in medicine, there is hope for a future where HIV can be effectively managed or even cured, but until then, zidovudine continues to be a beacon of hope for many.

齐多夫定，在中文中称为齐多夫定，是一种抗病毒药物，在HIV/AIDS的治疗中发挥了重要作用。该药物于1987年首次获得FDA批准，是用于对抗人类免疫缺陷病毒（HIV）的第一种药物。齐多夫定的开发标志着HIV治疗历史上的一个转折点，为数百万感染该病毒的人们带来了希望。它的主要功能是抑制逆转录酶，这对于HIV的复制至关重要。通过阻断这种酶，齐多夫定可以防止病毒繁殖，帮助降低体内的病毒载量。 齐多夫定的引入受到热烈欢迎，因为它是第一个有效的治疗选择。在其批准之前，HIV阳性患者的选择有限，面临着严峻的预后。然而，齐多夫定的出现改变了HIV治疗的格局，使患者能够更有效地管理他们的病情。它通常与其他抗病毒药物联合使用，以创建高度有效的抗逆转录病毒治疗（HAART）方案，这比单一药物更有效。 尽管有其好处，齐多夫定并非没有副作用。常见的不良反应包括恶心、头痛和疲劳。在某些情况下，长期使用齐多夫定可能导致更严重的并发症，例如骨髓抑制，这可能导致贫血和其他血液相关问题。因此，医疗提供者必须密切监测患者，并根据需要调整治疗计划以减轻这些风险。 齐多夫定的另一个关键方面是其在预防母婴传播HIV方面的作用。HIV阳性的孕妇可以服用齐多夫定，显著降低将病毒传给新生儿的风险。这在公共卫生领域是一次突破性的进展，因为它使得健康、HIV阴性婴儿的出生成为可能。 总之，齐多夫定代表了HIV/AIDS治疗的基石。虽然它有其局限性和潜在副作用，但它对受HIV影响人群生活的影响不可低估。随着研究的不断推进，新型和改进的治疗方法正在开发中，但齐多夫定仍然是对抗HIV的重要组成部分。理解齐多夫定的重要性及其在管理这种慢性疾病中的作用，对于医疗专业人员和患者来说都是至关重要的。随着医学的不断进步，人们对未来能够有效管理甚至治愈HIV充满希望，但在此之前，齐多夫定继续为许多人带来希望的曙光。